Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum

Neurodegeneration of the locus coeruleus (LC) in age-related neurodegenerative diseases such as Alzheimer’s disease (AD) is well-documented. However, detailed studies of LC neurodegeneration in the full spectrum of frontotemporal lobar degeneration (FTLD) proteinopathies comparing tauopathies (FTLD-...

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Veröffentlicht in:Acta Neuropathol
Hauptverfasser: Ohm, Daniel T., Peterson, Claire, Lobrovich, Rebecca, Cousins, Katheryn A.Q., Gibbons, Garrett S., McMillan, Corey T., Wolk, David A., Van Deerlin, Vivianna, Elman, Lauren, Spindler, Meredith, Deik, Andres, Siderowf, Andrew, Trojanowski, John Q., Lee, Edward B., Grossman, Murray, Irwin, David J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554264/
https://ncbi.nlm.nih.gov/pubmed/32804255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02210-1
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