ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration

INTRODUCTION: The ATN framework provides an in vivo diagnosis of Alzheimer’s disease (AD) using cerebrospinal fluid (CSF) biomarkers of pathologic amyloid plaques (A), tangles (T), and neurodegeneration (N). ATN is rarely evaluated in pathologically confirmed patients and its poor sensitivity to sus...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Cousins, Katheryn A.Q., Phillips, Jeffrey S., Irwin, David J., Lee, Edward B., Wolk, David A., Shaw, Leslie M., Zetterberg, Henrik, Blennow, Kaj, Burke, Sarah E., Kinney, Nikolas G., Gibbons, Garrett S., McMillan, Corey T., Trojanowski, John Q., Grossman, Murray
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8119305/
https://ncbi.nlm.nih.gov/pubmed/33226735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/alz.12233
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