Inhibition of Fatty Acid–Binding Protein 4 Attenuated Kidney Fibrosis by Mediating Macrophage-to-Myofibroblast Transition

The macrophage-to-myofibroblast transition (MMT) process is an important pathway that contributing to renal interstitial fibrosis (RIF). Fatty acid–binding protein 4 (FABP4) deteriorated RIF via promoting inflammation in obstructive nephropathy. However, the clinical significance of FABP4 in fibroti...

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Pubblicato in:Front Immunol
Autori principali: Feng, Yanhuan, Guo, Fan, Xia, Zijing, Liu, Jing, Mai, Hongxia, Liang, Yan, Zhu, Guonian, Li, Yanping, Bai, Lin, Li, Lingzhi, Huang, Rongshuang, Shi, Min, Ma, Liang, Fu, Ping
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7554244/
https://ncbi.nlm.nih.gov/pubmed/33101287
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.566535
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