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Macrophage-to-Myofibroblast Transition Contributes to Interstitial Fibrosis in Chronic Renal Allograft Injury

Interstitial fibrosis is an important contributor to graft loss in chronic renal allograft injury. Inflammatory macrophages are associated with fibrosis in renal allografts, but how these cells contribute to this damaging response is not clearly understood. Here, we investigated the role of macropha...

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Bibliographische Detailangaben
Veröffentlicht in:J Am Soc Nephrol
Hauptverfasser: Wang, Ying-Ying, Jiang, Hong, Pan, Jun, Huang, Xiao-Ru, Wang, Yu-Cheng, Huang, Hong-Feng, To, Ka-Fai, Nikolic-Paterson, David J., Lan, Hui-Yao, Chen, Jiang-Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Nephrology 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5491278/
https://ncbi.nlm.nih.gov/pubmed/28209809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2016050573
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