Neural transcription factor Pou4f1 promotes renal fibrosis via macrophage–myofibroblast transition

Unresolved inflammation can lead to tissue fibrosis and impaired organ function. Macrophage–myofibroblast transition (MMT) is one newly identified mechanism by which ongoing chronic inflammation causes progressive fibrosis in different forms of kidney disease. However, the mechanisms underlying MMT...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tang, Patrick Ming-Kuen, Zhang, Ying-ying, Xiao, Jun, Tang, Philip Chiu-Tsun, Chung, Jeff Yat-Fai, Li, Jinhong, Xue, Vivian Weiwen, Huang, Xiao-Ru, Chong, Charing Ching-Ning, Ng, Chi-Fai, Lee, Tin-Lap, To, Ka-Fai, Nikolic-Paterson, David J., Lan, Hui-Yao
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7456094/
https://ncbi.nlm.nih.gov/pubmed/32788346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1917663117
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