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Eplerenone Attenuates Fibrosis in the Contralateral Kidney of UUO Rats by Preventing Macrophage-to-Myofibroblast Transition

Severe renal fibrosis often occurs in obstructive kidney disease, not only in the obstructed kidney but also in the contralateral kidney, causing renal dysfunction. Although the mechanisms of injury in obstructed kidney have been studied for years, the pathogenesis of fibrosis in the contralateral k...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Xiong, Yunzhao, Chang, Yi, Hao, Juan, Zhang, Cuijuan, Yang, Fan, Wang, Zheng, Liu, Yunmeng, Wang, Xiangting, Mu, Shengyu, Xu, Qingyou
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7943730/
https://ncbi.nlm.nih.gov/pubmed/33716747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.620433
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