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Exploring the sequence fitness landscape of a bridge between protein folds

Most foldable protein sequences adopt only a single native fold. Recent protein design studies have, however, created protein sequences which fold into different structures apon changes of environment, or single point mutation, the best characterized example being the switch between the folds of the...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Tian, Pengfei, Best, Robert B.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553338/
https://ncbi.nlm.nih.gov/pubmed/33048928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008285
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