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Exploring the sequence fitness landscape of a bridge between protein folds

Most foldable protein sequences adopt only a single native fold. Recent protein design studies have, however, created protein sequences which fold into different structures apon changes of environment, or single point mutation, the best characterized example being the switch between the folds of the...

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Bibliografiske detaljer
Udgivet i:PLoS Comput Biol
Main Authors: Tian, Pengfei, Best, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553338/
https://ncbi.nlm.nih.gov/pubmed/33048928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1008285
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