Targeting the SARS-CoV-2 RNA Genome with Small Molecule Binders and Ribonuclease Targeting Chimera (RIBOTAC) Degraders

[Image: see text] COVID-19 is a global pandemic, thus requiring multiple strategies to develop modalities against it. Herein, we designed multiple bioactive small molecules that target a functional structure within the SARS-CoV-2’s RNA genome, the causative agent of COVID-19. An analysis to characte...

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Detaylı Bibliyografya
Yayımlandı:ACS Cent Sci
Asıl Yazarlar: Haniff, Hafeez S., Tong, Yuquan, Liu, Xiaohui, Chen, Jonathan L., Suresh, Blessy M., Andrews, Ryan J., Peterson, Jake M., O’Leary, Collin A., Benhamou, Raphael I., Moss, Walter N., Disney, Matthew D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2020
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7553039/
https://ncbi.nlm.nih.gov/pubmed/33140033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.0c00984
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