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Targeted Degradation of the Oncogenic MicroRNA 17–92 Cluster by Structure-Targeting Ligands
Many RNAs are processed into biologically active transcripts, the aberrant expression of which can contribute to disease phenotypes. For example, the primary microRNA-17–92 (pri-miR-17–92) cluster contains six microRNAs (miRNAs) that collectively act in several disease settings. Herein, we used sequ...
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| Publicado no: | J Am Chem Soc |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7357852/ https://ncbi.nlm.nih.gov/pubmed/32233464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.9b13159 |
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