MicroRNA 17-92 Cluster Mediates ETS1 and ETS2-Dependent RAS-Oncogenic Transformation

The ETS-family transcription factors Ets1 and Ets2 are evolutionarily conserved effectors of the RAS/ERK signaling pathway, but their function in Ras cellular transformation and biology remains unclear. Taking advantage of Ets1 and Ets2 mouse models to generate Ets1/Ets2 double knockout mouse embryo...

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Detalhes bibliográficos
Main Authors: Kabbout, Mohamed, Dakhlallah, Duaa, Sharma, Sudarshana, Bronisz, Agnieszka, Srinivasan, Ruchika, Piper, Melissa, Marsh, Clay B., Ostrowski, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4072627/
https://ncbi.nlm.nih.gov/pubmed/24968297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100693
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