Cellular senescence-mediated exacerbation of Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is a progressive disease characterised by chronic muscle degeneration and inflammation. Our previously established DMD model rats (DMD rats) have a more severe disease phenotype than the broadly used mouse model. We aimed to investigate the role of senescence in DMD...

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Udgivet i:Sci Rep
Main Authors: Sugihara, Hidetoshi, Teramoto, Naomi, Nakamura, Katsuyuki, Shiga, Takanori, Shirakawa, Taku, Matsuo, Masafumi, Ogasawara, Masashi, Nishino, Ichizo, Matsuwaki, Takashi, Nishihara, Masugi, Yamanouchi, Keitaro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550355/
https://ncbi.nlm.nih.gov/pubmed/33046751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73315-6
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