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Progranulin deficiency leads to prolonged persistence of macrophages, accompanied with myofiber hypertrophy in regenerating muscle

Skeletal muscle has an ability to regenerate in response to injury due to the presence of satellite cells. Injury in skeletal muscle causes infiltration of pro-inflammatory macrophages (M1 macrophages) to remove necrotic myofibers, followed by their differentiation into anti-inflammatory macrophages...

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Podrobná bibliografie
Vydáno v:J Vet Med Sci
Hlavní autoři: SUGIHARA, Hidetoshi, MIYAJI, Kei, YAMANOUCHI, Keitaro, MATSUWAKI, Takashi, NISHIHARA, Masugi
Médium: Artigo
Jazyk:Inglês
Vydáno: The Japanese Society of Veterinary Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836776/
https://ncbi.nlm.nih.gov/pubmed/29249750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.17-0638
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