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Progranulin deficiency leads to prolonged persistence of macrophages, accompanied with myofiber hypertrophy in regenerating muscle

Skeletal muscle has an ability to regenerate in response to injury due to the presence of satellite cells. Injury in skeletal muscle causes infiltration of pro-inflammatory macrophages (M1 macrophages) to remove necrotic myofibers, followed by their differentiation into anti-inflammatory macrophages...

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Bibliografski detalji
Izdano u:J Vet Med Sci
Glavni autori: SUGIHARA, Hidetoshi, MIYAJI, Kei, YAMANOUCHI, Keitaro, MATSUWAKI, Takashi, NISHIHARA, Masugi
Format: Artigo
Jezik:Inglês
Izdano: The Japanese Society of Veterinary Science 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5836776/
https://ncbi.nlm.nih.gov/pubmed/29249750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1292/jvms.17-0638
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