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Oxidative stress-mediated senescence in mesenchymal progenitor cells causes the loss of their fibro/adipogenic potential and abrogates myoblast fusion

Sarcopenia is the age-related loss of skeletal muscle mass and function. Skeletal muscle comprises diverse progenitor cells, including mesenchymal progenitor cells (MPCs), which normally support myogenic cell function but cause a decline in skeletal muscle function after differentiating into fibrous...

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Bibliografiske detaljer
Udgivet i:Aging (Albany NY)
Main Authors: Sugihara, Hidetoshi, Teramoto, Naomi, Yamanouchi, Keitaro, Matsuwaki, Takashi, Nishihara, Masugi
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5940129/
https://ncbi.nlm.nih.gov/pubmed/29695641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101425
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