Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAF(V600) melanoma cells

Identification of mechanisms underlying sensitivity and response to targeted therapies, such as the BRAF inhibitor vemurafenib, is critical in order to improve efficacy of these therapies in the clinic and delay onset of resistance. Glycolysis has emerged as a key feature of the BRAF inhibitor respo...

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Bibliographische Detailangaben
Veröffentlicht in:Sci Data
Hauptverfasser: Smith, Lorey K., Parmenter, Tiffany, Gould, Cathryn M., Madhamshettiwar, Piyush B., Sheppard, Karen E., Simpson, Kaylene J., McArthur, Grant A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550327/
https://ncbi.nlm.nih.gov/pubmed/33046726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-020-00683-z
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