Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAF(V600) melanoma cells

Identification of mechanisms underlying sensitivity and response to targeted therapies, such as the BRAF inhibitor vemurafenib, is critical in order to improve efficacy of these therapies in the clinic and delay onset of resistance. Glycolysis has emerged as a key feature of the BRAF inhibitor respo...

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發表在:Sci Data
Main Authors: Smith, Lorey K., Parmenter, Tiffany, Gould, Cathryn M., Madhamshettiwar, Piyush B., Sheppard, Karen E., Simpson, Kaylene J., McArthur, Grant A.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2020
主題:
Data Descriptor
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550327/
https://ncbi.nlm.nih.gov/pubmed/33046726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-020-00683-z
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