Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAF(V600) melanoma cells

Identification of mechanisms underlying sensitivity and response to targeted therapies, such as the BRAF inhibitor vemurafenib, is critical in order to improve efficacy of these therapies in the clinic and delay onset of resistance. Glycolysis has emerged as a key feature of the BRAF inhibitor respo...

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Detalhes bibliográficos
Publicado no:Sci Data
Main Authors: Smith, Lorey K., Parmenter, Tiffany, Gould, Cathryn M., Madhamshettiwar, Piyush B., Sheppard, Karen E., Simpson, Kaylene J., McArthur, Grant A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Data Descriptor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7550327/
https://ncbi.nlm.nih.gov/pubmed/33046726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41597-020-00683-z
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