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Cryo-EM structures reveal two distinct conformational states in a picornavirus cell entry intermediate
The virions of enteroviruses such as poliovirus undergo a global conformational change after binding to the cellular receptor, characterized by a 4% expansion, and by the opening of holes at the two and quasi-three-fold symmetry axes of the capsid. The resultant particle is called a 135S particle or...
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| Publicat a: | PLoS Pathog |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549760/ https://ncbi.nlm.nih.gov/pubmed/32997730 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1008920 |
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