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Catching a Virus in the Act of RNA Release: a Novel Poliovirus Uncoating Intermediate Characterized by Cryo-Electron Microscopy

Poliovirus infection requires that the particle undergo a series of conformational transitions that lead to cell entry and genome release. In an effort to understand the conformational changes associated with the release of the RNA genome, we have used cryo-electron microscopy to characterize the st...

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Detalhes bibliográficos
Main Authors: Levy, Hazel C., Bostina, Mihnea, Filman, David J., Hogle, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863768/
https://ncbi.nlm.nih.gov/pubmed/20181687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02393-09
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