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Cryo-Electron Microscopy Reconstruction Shows Poliovirus 135S Particles Poised for Membrane Interaction and RNA Release

During infection, binding of mature poliovirus to cell surface receptors induces an irreversible expansion of the capsid, to form an infectious cell-entry intermediate particle that sediments at 135S. In these expanded virions, the major capsid proteins (VP1 to VP3) adopt an altered icosahedral arra...

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Detalhes bibliográficos
Main Authors: Butan, Carmen, Filman, David J., Hogle, James M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3911577/
https://ncbi.nlm.nih.gov/pubmed/24257617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01949-13
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