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Catching a Virus in the Act of RNA Release: a Novel Poliovirus Uncoating Intermediate Characterized by Cryo-Electron Microscopy

Poliovirus infection requires that the particle undergo a series of conformational transitions that lead to cell entry and genome release. In an effort to understand the conformational changes associated with the release of the RNA genome, we have used cryo-electron microscopy to characterize the st...

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Autori principali: Levy, Hazel C., Bostina, Mihnea, Filman, David J., Hogle, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863768/
https://ncbi.nlm.nih.gov/pubmed/20181687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02393-09
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