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HIV Tat-mediated induction of autophagy regulates the disruption of ZO-1 in brain endothelial cells

The blood-brain barrier (BBB) is a tight barrier that is critical for preventing the entry of pathogens and small molecules into the brain. HIV protein Tat (Tat) is known to disrupt the tight junctions of the BBB. Autophagy is an intracellular process that involves degradation and recycling of damag...

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Bibliografiske detaljer
Udgivet i:Tissue Barriers
Main Authors: Liao, Ke, Niu, Fang, Hu, Guoku, Guo, Ming-Lei, Sil, Susmita, Buch, Shilpa
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549738/
https://ncbi.nlm.nih.gov/pubmed/32299282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21688370.2020.1748983
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