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HIV Tat-Mediated Induction of Human Brain Microvascular Endothelial Cell Apoptosis Involves Endoplasmic Reticulum Stress and Mitochondrial Dysfunction

Endoplasmic reticulum (ER) stress triggered under hyperglycemic, hypoxic, and oxidative conditions has been implicated in cellular dysfunction through activation of the unfolded protein response (UPR). Recent clinical studies have documented that the release of soluble cellular and host factors foll...

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Detalhes bibliográficos
Publicado no:Mol Neurobiol
Main Authors: Ma, Rong, Yang, Lu, Niu, Fang, Buch, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4787264/
https://ncbi.nlm.nih.gov/pubmed/25409632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8991-3
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