Homocysteine Induces Apoptosis of Human Umbilical Vein Endothelial Cells via Mitochondrial Dysfunction and Endoplasmic Reticulum Stress

Homocysteine- (Hcy-) induced endothelial cell apoptosis has been suggested as a cause of Hcy-dependent vascular injury, while the proposed molecular pathways underlying this process are unclear. In this study, we investigated the adverse effects of Hcy on human umbilical vein endothelial cells (HUVE...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Zhang, Zhimin, Wei, Congying, Zhou, Yanfen, Yan, Tao, Wang, Zhengqiang, Li, Wei, Zhao, Lianyou
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5467318/
https://ncbi.nlm.nih.gov/pubmed/28630659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/5736506
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