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HIV Tat 101-mediated loss of pericytes at the blood-brain barrier involves PDGF-BB

HIV-1-associated neurocognitive disorders (HAND) affect almost 30-50% of infected individuals, even in the presence of successful control of virus replication by combined antiretroviral therapy (cART).HIV Tat protein, a nuclear trans-activator of viral gene transcription, that is secreted by infecte...

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Detalhes bibliográficos
Publicado no:Ther Targets Neurol Dis
Main Authors: Niu, Fang, Yao, Honghong, Liao, Ke, Buch, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444060/
https://ncbi.nlm.nih.gov/pubmed/26023685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14800/ttnd.471
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