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PDGF-mediated protection of SH-SY5Y cells against Tat toxin involves regulation of extracellular glutamate and intracellular calcium

The human immunodeficiency virus (HIV-1) protein Tat has been implicated in mediating neuronal apoptosis, one of the hallmark features of HIV-associated dementia (HAD). Mitigation of the toxic effects of Tat could thus be a potential mechanism for reducing HIV toxicity in the brain. In this study we...

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Bibliografske podrobnosti
Main Authors: Zhu, Xuhui, Yao, Honghong, Peng, Fuwang, Callen, Shannon, Buch, Shilpa
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753679/
https://ncbi.nlm.nih.gov/pubmed/19576918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2009.06.020
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