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HIV-1 Tat-mediated astrocytic amyloidosis involves the HIF-1α/lncRNA BACE1-AS axis

Increased life expectancy of patients diagnosed with HIV in the current era of antiretroviral therapy is unfortunately accompanied with the prevalence of HIV-associated neurocognitive disorders (HANDs) and risk of comorbidities such as Alzheimer-like pathology. HIV-1 transactivator of transcription...

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Pubblicato in:PLoS Biol
Autori principali: Sil, Susmita, Hu, Guoku, Liao, Ke, Niu, Fang, Callen, Shannon, Periyasamy, Palsamy, Fox, Howard S., Buch, Shilpa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7274476/
https://ncbi.nlm.nih.gov/pubmed/32453744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.3000660
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