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HIV-1 Tat Primes and Activates Microglial NLRP3 Inflammasome-Mediated Neuroinflammation

Neuroinflammation associated with HIV-1 infection is a problem affecting ∼50% of HIV-infected individuals. NLR family pyrin domain containing 3 (NLRP3) inflammasome has been implicated in HIV-induced microglial activation, but the mechanism(s) remain unclear. Because HIV-1 Transactivator of Transcri...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Chivero, Ernest T., Guo, Ming-Lei, Periyasamy, Palsamy, Liao, Ke, Callen, Shannon E., Buch, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373137/
https://ncbi.nlm.nih.gov/pubmed/28270571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3045-16.2017
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