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The core spliceosomal factor U2AF1 controls cell-fate determination via the modulation of transcriptional networks

Alternative splicing (AS) plays a central role during cell-fate determination. However, how the core spliceosomal factors (CSFs) are involved in this process is poorly understood. Here, we report the down-regulation of the U2AF1 CSF during stem cell differentiation. To investigate its function in st...

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Detalhes bibliográficos
Publicado no:RNA Biol
Main Authors: Laaref, Abdelhamid Mahdi, Manchon, Laurent, Bareche, Yacine, Lapasset, Laure, Tazi, Jamal
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549707/
https://ncbi.nlm.nih.gov/pubmed/32150510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2020.1733800
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