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Stoichiometries of U2AF35, U2AF65 and U2 snRNP reveal new early spliceosome assembly pathways

The selection of 3΄ splice sites (3΄ss) is an essential early step in mammalian RNA splicing reactions, but the processes involved are unknown. We have used single molecule methods to test whether the major components implicated in selection, the proteins U2AF35 and U2AF65 and the U2 snRNP, are able...

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Detaylı Bibliyografya
Yayımlandı:Nucleic Acids Res
Asıl Yazarlar: Chen, Li, Weinmeister, Robert, Kralovicova, Jana, Eperon, Lucy P., Vorechovsky, Igor, Hudson, Andrew J., Eperon, Ian C.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
RNA
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389562/
https://ncbi.nlm.nih.gov/pubmed/27683217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw860
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