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Shedding new light on RhoA signalling as a drug target in vivo using a novel RhoA-FRET biosensor mouse
The small GTPase RhoA is a master regulator of signalling in cell-extracellular matrix interactions. RhoA signalling is critical to many cellular processes including migration, mechanotransduction, and is often disrupted in carcinogenesis. Investigating RhoA activity in a native tissue environment i...
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| Publicado no: | Small GTPases |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549666/ https://ncbi.nlm.nih.gov/pubmed/29457531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21541248.2018.1438024 |
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