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Peptoid NPhe(4) in AGRP-Based c[Pro(1)-Arg(2)-Phe(3)-Phe(4)-Xxx(5)-Ala(6)-Phe(7)-DPro(8)] Scaffolds Maintain Mouse MC4R Antagonist Potency
[Image: see text] The melanocortin receptors are involved in numerous physiological functions and are regulated by agonists derived from the proopiomelanocortin gene transcript and two endogenous antagonists, agouti and agouti-related protein (AGRP). The key binding and functional determinant of AGR...
Guardado en:
| Publicado en: | ACS Med Chem Lett |
|---|---|
| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7549258/ https://ncbi.nlm.nih.gov/pubmed/33062177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00641 |
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