Targeted Detection of Cyclooxygenase-1 in Ovarian Cancer

[Image: see text] Overexpression of cyclooxygenase-1 (COX-1) is associated with the initiation and progression of ovarian cancer, and targeted imaging of COX-1 is a promising strategy for early detection of this disease. We report the discovery of N-[(5-carboxy-X-rhodaminyl)but-4-yl]-3-(1-(4-methoxy...

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Detalhes bibliográficos
Publicado no:ACS Med Chem Lett
Main Authors: Malerba, Paola, Crews, Brenda C., Ghebreselasie, Kebreab, Daniel, Cristina K., Jashim, Elma, Aleem, Ansari M., Salam, Redoan A., Marnett, Lawrence J., Uddin, Md. Jashim
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7549111/
https://ncbi.nlm.nih.gov/pubmed/33062161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00280
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