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Bidirectional Direct Sequencing of Noncanonical RNA by Two-Dimensional Analysis of Mass Chromatograms

[Image: see text] Mass spectrometry (MS) is a powerful technique for characterizing noncanonical nucleobases and other chemical modifications in small RNAs, yielding rich chemical information that is complementary to high-throughput indirect sequencing. However, mass spectra are often prohibitively...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Björkbom, Anders, Lelyveld, Victor S., Zhang, Shenglong, Zhang, Weicheng, Tam, Chun Pong, Blain, J. Craig, Szostak, Jack W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2015
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547889/
https://ncbi.nlm.nih.gov/pubmed/26495937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b09438
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