Downstream Oligonucleotides Strongly Enhance the Affinity of GMP to RNA Primer–Template Complexes

[Image: see text] Origins of life hypotheses often invoke a transitional phase of nonenzymatic template-directed RNA replication prior to the emergence of ribozyme-catalyzed copying of genetic information. Here, using NMR and ITC, we interrogate the binding affinity of guanosine 5′-monophosphate (GM...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Tam, Chun Pong, Fahrenbach, Albert C., Björkbom, Anders, Prywes, Noam, Izgu, Enver Cagri, Szostak, Jack W.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Chemical Society 2017
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547879/
https://ncbi.nlm.nih.gov/pubmed/28055190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09760
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk