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The KDEL trafficking receptor exploits pH to tune the strength of an unusual short hydrogen bond

The endoplasmic reticulum (ER) is the main site of protein synthesis in eukaryotic cells and requires a high concentration of luminal chaperones to function. During protein synthesis, ER luminal chaperones are swept along the secretory pathway and must be retrieved to maintain cell viability. ER pro...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Wu, Zhiyi, Newstead, Simon, Biggin, Philip C.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547670/
https://ncbi.nlm.nih.gov/pubmed/33037300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-73906-3
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