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Current landscape of treatments for Wolfram syndrome

Wolfram syndrome is a rare genetic spectrum disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy and progressive neurodegeneration and ranges from mild to severe clinical symptoms. There is currently no treatment to delay, halt, or reverse the progression of Wolfram syn...

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Publicado en:Trends Pharmacol Sci
Main Authors: Abreu, Damien, Urano, Fumihiko
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547529/
https://ncbi.nlm.nih.gov/pubmed/31420094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.07.011
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