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Current landscape of treatments for Wolfram syndrome

Wolfram syndrome is a rare genetic spectrum disorder characterized by insulin-dependent diabetes mellitus, optic nerve atrophy and progressive neurodegeneration and ranges from mild to severe clinical symptoms. There is currently no treatment to delay, halt, or reverse the progression of Wolfram syn...

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Publicat a:Trends Pharmacol Sci
Autors principals: Abreu, Damien, Urano, Fumihiko
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547529/
https://ncbi.nlm.nih.gov/pubmed/31420094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2019.07.011
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