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Wolfram syndrome 1 gene regulates pathways maintaining beta cell health and survival
Wolfram Syndrome 1 (WFS1) protein is an endoplasmic reticulum (ER) factor whose deficiency results in juvenile-onset diabetes secondary to cellular dysfunction and apoptosis. The mechanisms guiding β-cell outcomes secondary to WFS1 function, however, remain unclear. Here, we show that WFS1 preserves...
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| Publicat a: | Lab Invest |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7286786/ https://ncbi.nlm.nih.gov/pubmed/32060407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41374-020-0408-5 |
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