Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery

Intercellular communication between tumor cells within the hypoxic microenvironment promote aggressiveness and poor patient prognoses for reasons that remain unclear. Here we show that hypoxic Ewing’s sarcoma (EWS) cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS c...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Kling, Matthew J., Chaturvedi, Nagendra K., Kesherwani, Varun, Coulter, Don W., McGuire, Timothy R., Sharp, J. Graham, Joshi, Shantaram S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546758/
https://ncbi.nlm.nih.gov/pubmed/33088424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27702
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky