Exosomes secreted under hypoxia enhance stemness in Ewing’s sarcoma through miR-210 delivery

Intercellular communication between tumor cells within the hypoxic microenvironment promote aggressiveness and poor patient prognoses for reasons that remain unclear. Here we show that hypoxic Ewing’s sarcoma (EWS) cells release exosomes that promote sphere formation, a stem-like phenotype, in EWS c...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Kling, Matthew J., Chaturvedi, Nagendra K., Kesherwani, Varun, Coulter, Don W., McGuire, Timothy R., Sharp, J. Graham, Joshi, Shantaram S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2020
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546758/
https://ncbi.nlm.nih.gov/pubmed/33088424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27702
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