Improved therapy for medulloblastoma: targeting hedgehog and PI3K-mTOR signaling pathways in combination with chemotherapy

Aberrant activation and interactions of hedgehog (HH) and PI3K/AKT/mTOR signaling pathways are frequently associated with high-risk medulloblastoma (MB). Thus, combined targeting of the HH and PI3K/AKT/mTOR pathways could be a viable therapeutic strategy to treat high-risk patients. Therefore, we in...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chaturvedi, Nagendra K., Kling, Matthew J., Coulter, Don W., McGuire, Timothy R., Ray, Sutapa, Kesherwani, Varun, Joshi, Shantaram S., Sharp, J. Graham
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908274/
https://ncbi.nlm.nih.gov/pubmed/29682173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24618
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados