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The pro-apoptotic actions of 2-methoxyestradiol against ovarian cancer involve catalytic activation of PKCδ signaling

Background: 2-methoxyestradiol (2MeOE(2)) is a natural metabolite of estradiol, which is generated by the action of CYP1A1 enzyme in the liver. We have previously shown that a flaxseed-supplemented diet decreases both the incidence and severity of ovarian cancer in laying hens, also induces CYP1A1 e...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Pal, Purab, Hales, Karen, Hales, Dale Buchanan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546757/
https://ncbi.nlm.nih.gov/pubmed/33088425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.27760
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