PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy

NADPH oxidase is the major source of superoxide production in cardiovascular tissues. We reported previously that PG (prostaglandin) F2α caused hypertrophy of vascular smooth muscle cells by induction of NOX1, a catalytic subunit of NADPH oxidase. PGF2α-induced NOX1 expression was mediated by transa...

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Главные авторы: Fan, Chun Yuan, Katsuyama, Masato, Yabe-Nishimura, Chihiro
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2005
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199669/
https://ncbi.nlm.nih.gov/pubmed/15913451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050287
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