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PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy
NADPH oxidase is the major source of superoxide production in cardiovascular tissues. We reported previously that PG (prostaglandin) F2α caused hypertrophy of vascular smooth muscle cells by induction of NOX1, a catalytic subunit of NADPH oxidase. PGF2α-induced NOX1 expression was mediated by transa...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Portland Press Ltd.
2005
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1199669/ https://ncbi.nlm.nih.gov/pubmed/15913451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050287 |
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