PKCδ mediates up-regulation of NOX1, a catalytic subunit of NADPH oxidase, via transactivation of the EGF receptor: possible involvement of PKCδ in vascular hypertrophy

NADPH oxidase is the major source of superoxide production in cardiovascular tissues. We reported previously that PG (prostaglandin) F2α caused hypertrophy of vascular smooth muscle cells by induction of NOX1, a catalytic subunit of NADPH oxidase. PGF2α-induced NOX1 expression was mediated by transa...

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Autors principals: Fan, Chun Yuan, Katsuyama, Masato, Yabe-Nishimura, Chihiro
Format: Artigo
Idioma:Inglês
Publicat: Portland Press Ltd. 2005
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1199669/
https://ncbi.nlm.nih.gov/pubmed/15913451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20050287
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