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Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC

Conflicting roles for protein kinase C (PKC) isozymes in cardiac disease have been reported. Here, δPKC-selective activator and inhibitor peptides were designed rationally, based on molecular modeling and structural homology analyses. Together with previously identified activator and inhibitor pepti...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Chen, Leon, Hahn, Harvey, Wu, Guangyu, Chen, Che-Hong, Liron, Tamar, Schechtman, Deborah, Cavallaro, Gabriele, Banci, Lucia, Guo, Yiru, Bolli, Roberto, Dorn, Gerald W., Mochly-Rosen, Daria
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC58692/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11553773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.191369098
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