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Opposing cardioprotective actions and parallel hypertrophic effects of δPKC and ɛPKC
Conflicting roles for protein kinase C (PKC) isozymes in cardiac disease have been reported. Here, δPKC-selective activator and inhibitor peptides were designed rationally, based on molecular modeling and structural homology analyses. Together with previously identified activator and inhibitor pepti...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC58692/ https://ncbi.nlm.nih.gov/pubmed/11553773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191369098 |
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