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δPKC inhibition or εPKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification

The balance between endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) and reactive oxygen species (ROS) production determines endothelial-mediated vascular homeostasis. Activation of protein kinase C (PKC) has been linked to imbalance of the eNOS/ROS system, which leads to endotheli...

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Bibliographic Details
Main Authors: Monti, Martina, Donnini, Sandra, Giachettia, Antonio, Mochly-Rosen, Daria, Zichea, Marina
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3760592/
https://ncbi.nlm.nih.gov/pubmed/19913548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.11.002
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