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δPKC inhibition or εPKC activation repairs endothelial vascular dysfunction by regulating eNOS post-translational modification
The balance between endothelial nitric oxide synthase (eNOS)-derived nitric oxide (NO) and reactive oxygen species (ROS) production determines endothelial-mediated vascular homeostasis. Activation of protein kinase C (PKC) has been linked to imbalance of the eNOS/ROS system, which leads to endotheli...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3760592/ https://ncbi.nlm.nih.gov/pubmed/19913548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2009.11.002 |
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