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Hyperhomocystinemia Impairs Endothelial Function and eNOS Activity via PKC Activation

OBJECTIVE: A risk factor for cardiovascular disease, hyperhomocystinemia (HHcy), is associated with endothelial dysfunction. In this study, we examined the mechanistic role of HHcy in endothelial dysfunction. METHODS AND RESULTS: Through the use of 2 functional models, aortic rings and intravital vi...

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Detalhes bibliográficos
Publicado no:Arterioscler Thromb Vasc Biol
Main Authors: Jiang, Xiaohua, Yang, Fan, Tan, Hongmei, Liao, Dan, Bryan, Robert M., Randhawa, Jaspreet K., Rumbaut, Rolando E., Durante, William, Schafer, Andrew I., Yang, Xiaofeng, Wang, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4400833/
https://ncbi.nlm.nih.gov/pubmed/16210565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/01.ATV.0000189559.87328.e4
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