Matrine Inhibits CNS Autoimmunity Through an IFN-β-Dependent Mechanism

Matrine (MAT), a quinolizidine alkaloid component derived from the root of Sophora flavescens, suppresses experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), by inducing the production of immunomodulatory molecules, e.g., IL-10. In an effort to find the upst...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Chu, Yao-Juan, Ma, Wen-Di, Thome, Rodolfo, Ping, Jie-Dan, Liu, Fang-Zhou, Wang, Meng-Ru, Zhang, Ming-Liang, Zhang, Guangxian, Zhu, Lin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2020
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7546369/
https://ncbi.nlm.nih.gov/pubmed/33101289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.569530
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