IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells

IFN-β has been the treatment for multiple sclerosis (MS) for almost three decades, but understanding the mechanisms underlying its beneficial effects remains incomplete. We have shown that MS patients have increased numbers of GM-CSF(+) Th cells in circulation, and that IFN-β therapy reduces their n...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Front Immunol
Κύριοι συγγραφείς: Rasouli, Javad, Casella, Giacomo, Ishikawa, Larissa L. W., Thome, Rodolfo, Boehm, Alexandra, Ertel, Adam, Melo-Silva, Carolina R., Mari, Elisabeth R., Porazzi, Patrizia, Zhang, Weifeng, Xiao, Dan, Sigal, Luis J., Fortina, Paolo, Zhang, Guang-Xian, Rostami, Abdolmohamad, Ciric, Bogoljub
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Frontiers Media S.A. 2021
Θέματα:
Immunology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213026/
https://ncbi.nlm.nih.gov/pubmed/34149716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679498
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