IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells

IFN-β has been the treatment for multiple sclerosis (MS) for almost three decades, but understanding the mechanisms underlying its beneficial effects remains incomplete. We have shown that MS patients have increased numbers of GM-CSF(+) Th cells in circulation, and that IFN-β therapy reduces their n...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Front Immunol
Huvudupphovsmän: Rasouli, Javad, Casella, Giacomo, Ishikawa, Larissa L. W., Thome, Rodolfo, Boehm, Alexandra, Ertel, Adam, Melo-Silva, Carolina R., Mari, Elisabeth R., Porazzi, Patrizia, Zhang, Weifeng, Xiao, Dan, Sigal, Luis J., Fortina, Paolo, Zhang, Guang-Xian, Rostami, Abdolmohamad, Ciric, Bogoljub
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Immunology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213026/
https://ncbi.nlm.nih.gov/pubmed/34149716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679498
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk