IFN-β Acts on Monocytes to Ameliorate CNS Autoimmunity by Inhibiting Proinflammatory Cross-Talk Between Monocytes and Th Cells

IFN-β has been the treatment for multiple sclerosis (MS) for almost three decades, but understanding the mechanisms underlying its beneficial effects remains incomplete. We have shown that MS patients have increased numbers of GM-CSF(+) Th cells in circulation, and that IFN-β therapy reduces their n...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Rasouli, Javad, Casella, Giacomo, Ishikawa, Larissa L. W., Thome, Rodolfo, Boehm, Alexandra, Ertel, Adam, Melo-Silva, Carolina R., Mari, Elisabeth R., Porazzi, Patrizia, Zhang, Weifeng, Xiao, Dan, Sigal, Luis J., Fortina, Paolo, Zhang, Guang-Xian, Rostami, Abdolmohamad, Ciric, Bogoljub
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8213026/
https://ncbi.nlm.nih.gov/pubmed/34149716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.679498
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares