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Matrine Inhibits CNS Autoimmunity Through an IFN-β-Dependent Mechanism
Matrine (MAT), a quinolizidine alkaloid component derived from the root of Sophora flavescens, suppresses experimental autoimmune encephalomyelitis (EAE), the animal model of multiple sclerosis (MS), by inducing the production of immunomodulatory molecules, e.g., IL-10. In an effort to find the upst...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Frontiers Media S.A.
2020-09-01
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Colecção: | Frontiers in Immunology |
Assuntos: | |
Acesso em linha: | https://www.frontiersin.org/article/10.3389/fimmu.2020.569530/full |
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